Posts

Showing posts from December, 2012

Genes, brains and lateralisation: how solid is the evidence?

Image
If there were a dictionary of famous neurological quotes, “Nous parlons avec l'hémisphère gauche” by Paul Broca (1865) would be up there among the top hits. Broca’s realisation that the two sides of the brain are functionally distinct was a landmark observation. It was based on a rather small series of patients, but has since been confirmed in numerous studies. After localised brain injury, aphasia (language impairment) is far more likely after damage to the left side than the right side. And nowadays, we can visualise greater activation of the left side in neurologically intact people as they do language tasks in a brain scanner. There are many fascinating features of cerebral lateralisation, but I’m going to focus here on just one specific question: what do we know about genetic influences on brain asymmetry in humans?  There are really two questions here: (1) how do genes lead to asymmetric brain development? (2) are there genetic variants that can account for individual variat...

Psychology: Where are all the men?

Image
There's a lot of interest in under-representation of women in certain science subjects, but in psychology, there's more concern about a lack of men. A quick look at figures from UCAS* (Universities & Colleges Admissions Service) shows massive differences in gender ratios for different subjects. In figure 1 I’ve plotted the percentage of women accepted for subjects that had at least 6000 successful applicants to degree courses in 2011. Fig. 1. % Females accepted on popular UK degree courses 2011 Given the large sample sizes, the sex differences are statistically significant for all subjects except Media Studies, which is bang on 50%. As a psychologist, I found the most surprising thing about this plot was the huge preponderance of women in psychology. This didn’t square with my experiences: my colleagues include a good mix of men and women, so I was keen to find the explanation for the mismatch. There seemed to be several possible explanations, which aren’t mutually exclusi...